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Displaying record number 61245

HXB2 Location Gag(180-188) Gag Epitope Map
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Epitope

TPQDLNTML

Epitope Alignment

Variants

TPaDLNTML HLA association; observed variant

Epitope Name TL9, TL9T7

Species (MHC/HLA) human(B*42:01, B*81:01)

Variant Details

Showing 1 of 5 variants.

Variant ID.	`3757`
Epitope Seq.	`TPQDLNTML`
Variant Seq.	`TPaDLNTML`
Mutations	Q/A
Epitope Location	Q3A
HXB2 Location	Q182A
Mutation Type	A: HLA association OV: observed variant
Epitope Subtype	B, C, D, F, G, J, K
Variant Subtype	C
Method	Other
Note	Variant, TPaDLNTML, is present in 7.1% of B42⁺ subjects; 2.5% of B42^-/B*81^- subjects.

References

Geldmacher2009 Christof Geldmacher, Ian S. Metzler, Sodsai Tovanabutra, Tedi E. Asher, Emma Gostick, David R. Ambrozak, Constantinos Petrovas, Alexandra Schuetz, Njabulo Ngwenyama, Gustavo Kijak, Leonard Maboko, Michael Hoelscher, Francine McCutchan, David A. Price, Daniel C. Douek, and Richard A. Koup. Minor Viral and Host Genetic Polymorphisms Can Dramatically Impact the Biologic Outcome of an Epitope-Specific CD8 T-Cell Response. Blood, 114(8):1553-1562, 20 Aug 2009. PubMed ID: 19542300. Show all entries for this paper.