HIV molecular immunology database
Found 1 matching record:
HXB2 Location | Gag(140-147) | Gag Epitope Map
View variants at this location |
||||
---|---|---|---|---|---|---|
Epitope |
GQMVHQAI
|
Epitope Alignment | ||||
Variants |
|
|||||
Epitope Name | GI8 | |||||
Species (MHC/HLA) | human(B*13:02) |
Showing 1 of 2 variants.
Variant ID. | 3748 |
---|---|
Epitope Seq. | GQMVHQAI |
Variant Seq. | GQMVHQsI |
Mutations | A/S |
Epitope Location | A7S |
HXB2 Location | A146S |
Mutation Type | A: HLA association E: escape documented in this paper |
Epitope Subtype | B |
Variant Subtype | B |
Method | Relative replication capacity assay |
Note | Mutation A146S in epitope GQMVHQAI, i.e. GQMVHQsI, is associated with HLA-B*13/1302. |
Shahid2015 Aniqa Shahid, Alex Olvera, Gursev Anmole, Xiaomei T. Kuang, Laura A. Cotton, Montserrat Plana, Christian Brander, Mark A. Brockman, and Zabrina L. Brumme. Consequences of HLA-B*13-Associated Escape Mutations on HIV-1 Replication and Nef Function. J. Virol., 89(22):11557-11571, Nov 2015. PubMed ID: 26355081. Show all entries for this paper.