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Found 1 matching record:

Displaying record number 61204

HXB2 Location  Gag(22-30)   Gag Epitope Map
View variants at this location
Epitope RPGGKKHYM   Epitope Alignment
Variants
RPGGKKqYM   escape documented in this paper; replicative capacity reduced
Epitope Name RM9
Species (MHC/HLA human(B*07:02, B*42:01)

Variant Details

Showing 1 of 4 variants.


Variant ID.  3710
Epitope Seq.  RPGGKKHYM
Variant Seq.  RPGGKKqYM
Mutations H/Q
Epitope Location H7Q
HXB2 Location H28Q
Mutation Type E: escape documented in this paper
RCR: replicative capacity reduced
Epitope Subtype B
Variant Subtype B
Method Other
Note RPGGKKqYM is an escape variant of RPGGKKHYM that reduces VRC.

References

Kloverpris2015a Henrik N. Kløverpris, Alasdair Leslie, and Philip Goulder. Role of HLA Adaptation in HIV Evolution. Front. Immunol., 6:665, 18 Jan 2016. PubMed ID: 26834742. Show all entries for this paper.


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