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Found 1 matching record:

Displaying record number 61203

HXB2 Location  Gag(180-188)   Gag Epitope Map
View variants at this location
Epitope TPQDLNTML   Epitope Alignment
Variants
TPeDLNTML   escape documented in this paper; replicative capacity reduced
Epitope Name TL9
Species (MHC/HLA human(B*07:02, B*39:10, B*42:01, B*81:01, C*08:02)

Variant Details

Showing 1 of 5 variants.


Variant ID.  3706
Epitope Seq.  TPQDLNTML
Variant Seq.  TPeDLNTML
Mutations Q/E
Epitope Location Q3E
HXB2 Location Q182E
Mutation Type E: escape documented in this paper
RCR: replicative capacity reduced
Epitope Subtype B
Variant Subtype B
Method Other
Note TPeDLNTML is an escape variant of TPQDLNTML that reduces VRC.

References

Kloverpris2015a Henrik N. Kløverpris, Alasdair Leslie, and Philip Goulder. Role of HLA Adaptation in HIV Evolution. Front. Immunol., 6:665, 18 Jan 2016. PubMed ID: 26834742. Show all entries for this paper.


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