Search the Epitope Variant and Escape Mutation Database

Help

Found 1 matching record:

Displaying record number 61193

HXB2 Location Gag(114-122) Gag Epitope Map
View variants at this location

Epitope

KTQQAAADK

Epitope Alignment

Variants

KaQQAAADt observed variant

Species (MHC/HLA) human, mouse(B*57)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`3597`
Epitope Seq.	`KTQQAAADK`
Variant Seq.	`KaQQAAADt`
Mutations	T/A K/T
Epitope Location	T2A K9T
HXB2 Location	T115A K122T
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	Other
Note	Vaccine-included variant KaQQAAADt is present in a highly variable region of Gag p17 and forms 11% of 4,300 database sequences.

References

Ondondo2016 Beatrice Ondondo, Hayato Murakoshi, Genevieve Clutton, Sultan Abdul-Jawad, Edmund G.-T. Wee, Hiroyuki Gatanaga, Shinichi Oka, Andrew J. McMichael, Masafumi Takiguchi, Bette Korber, and Tomáš Hanke. Novel Conserved-region T-cell Mosaic Vaccine With High Global HIV-1 Coverage Is Recognized by Protective Responses in Untreated Infection. Mol. Ther., 24(4):832-842, Apr 2016. PubMed ID: 26743582. Show all entries for this paper.