HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 61031

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLfNTVAvL   subtype-specific susceptible form
Epitope Name SL9
Species (MHC/HLA human(A*02:01)

Variant Details

Showing 1 of 7 variants.


Variant ID.  3564
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTVAvL
Mutations Y/F T/V
Epitope Location Y3F T8V
HXB2 Location Y79F T84V
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype A
Method CD8 T-cell Elispot - IFNy, Other
Note Vaiant SLfNTVAvL was also recognized on CD4+ T cells by ImmTAVs m121 and m134.

References

Yang2016 Hongbing Yang, Sandrine Buisson, Giovanna Bossi, Zoë Wallace, Gemma Hancock, Chun So, Rebecca Ashfield, Annelise Vuidepot, Tara Mahon, Peter Molloy, Joanne Oates, Samantha J. Paston, Milos Aleksic, Namir J. Hassan, Bent K. Jakobsen, and Lucy Dorrell. Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-Suppressed Subjects by Engineered Immune-Mobilizing T-Cell Receptors. Mol. Ther., 24(11):1913-1925, Nov 2016. PubMed ID: 27401039. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health