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Displaying record number 61031

HXB2 Location Gag(77-85) Gag Epitope Map
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Epitope

SLYNTVATL

Epitope Alignment

Variants

SLYNIiAvL subtype-specific susceptible form

Epitope Name SL9

Species (MHC/HLA) human(A*02:01)

Variant Details

Showing 1 of 7 variants.

Variant ID.	`3560`
Epitope Seq.	`SLYNTVATL`
Variant Seq.	`SLYNIiAvL`
Mutations	T/I V/I T/V
Epitope Location	T5I V6I T8V
HXB2 Location	T81I V82I T84V
Mutation Type	SSF: subtype-specific susceptible form
Epitope Subtype	B
Variant Subtype	A
Method	CD8 T-cell Elispot - IFNy, Other
Note	Vaiant SLYNIiAvL was also recognized on CD4+ T cells by ImmTAVs m121 and m134.

References

Yang2016 Hongbing Yang, Sandrine Buisson, Giovanna Bossi, Zoë Wallace, Gemma Hancock, Chun So, Rebecca Ashfield, Annelise Vuidepot, Tara Mahon, Peter Molloy, Joanne Oates, Samantha J. Paston, Milos Aleksic, Namir J. Hassan, Bent K. Jakobsen, and Lucy Dorrell. Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-Suppressed Subjects by Engineered Immune-Mobilizing T-Cell Receptors. Mol. Ther., 24(11):1913-1925, Nov 2016. PubMed ID: 27401039. Show all entries for this paper.