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Displaying record number 60672

HXB2 Location Gag(28-36) Gag Epitope Map
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Epitope

RYRLKHLVW

Epitope Alignment

Variants

kYRLKHiVW observed variant; susceptible form

Species (MHC/HLA) human(A*24:02)

Variant Details

Showing 1 of 2 variants.

Variant ID.	`3555`
Epitope Seq.	`RYRLKHLVW`
Variant Seq.	`kYRLKHiVW`
Mutations	R/K L/I
Epitope Location	R1K L7I
HXB2 Location	R28K L34I
Mutation Type	OV: observed variant SF: susceptible form
Epitope Subtype	B
Variant Subtype	B
Method	CD8 T-cell Elispot - IFNy, Other
Note	Autologous variant Gag kYRLKHiVW of subject S2 also elicits a greater CTL response from DC-primed naive T cells than DC-stimulated memory T cells.

References

Smith2016 Kellie N. Smith, Robbie B. Mailliard, Paolo A. Piazza, Will Fischer, Bette T. Korber, Ronald J. Fecek, Deena Ratner, Phalguni Gupta, James I. Mullins, and Charles R. Rinaldo. Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells. MBio, 7(3), 31 May 2016. PubMed ID: 27247230. Show all entries for this paper.