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Found 1 matching record:

Displaying record number 60672

HXB2 Location  Gag(28-36)   Gag Epitope Map
View variants at this location
Epitope RYRLKHLVW   Epitope Alignment
Variants
kYRLKHiVW   observed variant; susceptible form
Species (MHC/HLA human(A*24:02)

Variant Details

Showing 1 of 2 variants.


Variant ID.  3555
Epitope Seq.  RYRLKHLVW
Variant Seq.  kYRLKHiVW
Mutations R/K L/I
Epitope Location R1K L7I
HXB2 Location R28K L34I
Mutation Type OV: observed variant
SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Other
Note Autologous variant Gag kYRLKHiVW of subject S2 also elicits a greater CTL response from DC-primed naive T cells than DC-stimulated memory T cells.

References

Smith2016 Kellie N. Smith, Robbie B. Mailliard, Paolo A. Piazza, Will Fischer, Bette T. Korber, Ronald J. Fecek, Deena Ratner, Phalguni Gupta, James I. Mullins, and Charles R. Rinaldo. Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells. MBio, 7(3), 31 May 2016. PubMed ID: 27247230. Show all entries for this paper.


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