HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 60671

HXB2 Location  Gag(28-36)   Gag Epitope Map
View variants at this location
Epitope QYKLKHIVW   Epitope Alignment
kYrLKHIVW   observed variant; susceptible form
Species (MHC/HLA human(A*24:02)

Variant Details

Showing 1 of 2 variants.

Variant ID.  3553
Epitope Seq.  QYKLKHIVW
Variant Seq.  kYrLKHIVW
Mutations Q/K K/R
Epitope Location Q1K K3R
HXB2 Location Q28K K30R
Mutation Type OV: observed variant
SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Other
Note Autologous variant Gag kYrLKHIVW of subject S2 also elicits a greater CTL response from DC-primed naive T cells than DC-stimulated memory T cells.


Smith2016 Kellie N. Smith, Robbie B. Mailliard, Paolo A. Piazza, Will Fischer, Bette T. Korber, Ronald J. Fecek, Deena Ratner, Phalguni Gupta, James I. Mullins, and Charles R. Rinaldo. Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells. MBio, 7(3), 31 May 2016. PubMed ID: 27247230. Show all entries for this paper.

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