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Found 1 matching record:

Displaying record number 169

HXB2 Location  Gag(167-175)   Gag Epitope Map
View variants at this location
Epitope EVIPMFSAL   Epitope Alignment
Variants
EVIPMFaAL   observed variant
Species (MHC/HLA human(A*26:01)

Variant Details

Showing 1 of 2 variants.


Variant ID.  355
Epitope Seq.  EVIPMFSAL
Variant Seq.  EVIPMFaAL
Mutations S/A
Epitope Location S7A
HXB2 Location S173A
Mutation Type OV: observed variant
Note 14 of 70 sequences had a conservative change at this position, either to A or to T. Only one subtype B sequence had this epitope variant.

References

Goulder1996b P. Goulder, C. Conlon, K. McIntyre, and A. McMichael. Identification of a Novel Human Leukogen Antigen A26-Restricted Epitope in a Conserved Region of Gag. AIDS, 10(12):1441-1443, 1996. This paper is correspondence briefly describing the identification and characterization of an immunodominant A26-CTL epitope in an asymptomatic HIV+ individual. PubMed ID: 8902082. Show all entries for this paper.


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