HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
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| Epitope |
SLYNTVATL
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | A2-SL9 | |||||
| Species (MHC/HLA) | human | |||||
Showing 1 of 5 variants.
| Variant ID. | 3506 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLfNaVAvL |
| Mutations | Y/F T/A T/V |
| Epitope Location | Y3F T5A T8V |
| HXB2 Location | Y79F T81A T84V |
| Mutation Type | A: HLA association TCR: TCR related mutation |
| Method | Other, Tetramer binding |
| Note | At t1, subject 2 (ACS 19957) carried 100% SLfNaVAvL, which decreased to 6.3% with reversion of T81A to T at t2. |
Costa2015 Ana I. Costa, Dan Koning, Kristin Ladell, James E. McLaren, Bart P. X. Grady, Ingrid M. M. Schellens, Petra van Ham, Monique Nijhuis, José A. M. Borghans, Can Keşmir, David A. Price, and Debbie van Baarle. Complex T-Cell Receptor Repertoire Dynamics Underlie the CD8+ T-Cell Response to HIV-1. J. Virol., 89(1):110-119, Jan 2015. PubMed ID: 25320304. Show all entries for this paper.