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Found 1 matching record:

Displaying record number 60505

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLfNaVAvL   HLA association; TCR related mutation
Epitope Name A2-SL9
Species (MHC/HLA human

Variant Details

Showing 1 of 5 variants.


Variant ID.  3506
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNaVAvL
Mutations Y/F T/A T/V
Epitope Location Y3F T5A T8V
HXB2 Location Y79F T81A T84V
Mutation Type A: HLA association
TCR: TCR related mutation
Method Other, Tetramer binding
Note At t1, subject 2 (ACS 19957) carried 100% SLfNaVAvL, which decreased to 6.3% with reversion of T81A to T at t2.

References

Costa2015 Ana I. Costa, Dan Koning, Kristin Ladell, James E. McLaren, Bart P. X. Grady, Ingrid M. M. Schellens, Petra van Ham, Monique Nijhuis, José A. M. Borghans, Can Keşmir, David A. Price, and Debbie van Baarle. Complex T-Cell Receptor Repertoire Dynamics Underlie the CD8+ T-Cell Response to HIV-1. J. Virol., 89(1):110-119, Jan 2015. PubMed ID: 25320304. Show all entries for this paper.


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