HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 60505

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLYNTiATL   HLA association; TCR related mutation
Epitope Name A2-SL9
Species (MHC/HLA human

Variant Details

Showing 1 of 5 variants.


Variant ID.  3504
Epitope Seq.  SLYNTVATL
Variant Seq.  SLYNTiATL
Mutations V/I
Epitope Location V6I
HXB2 Location V82I
Mutation Type A: HLA association
TCR: TCR related mutation
Method Other, Tetramer binding
Note At t2, subject 1 (ACS 19957) carried 100% SLYNTiATL while subject 7 (AC 18839) had 9.7% of this variant by t2.

References

Costa2015 Ana I. Costa, Dan Koning, Kristin Ladell, James E. McLaren, Bart P. X. Grady, Ingrid M. M. Schellens, Petra van Ham, Monique Nijhuis, José A. M. Borghans, Can Keşmir, David A. Price, and Debbie van Baarle. Complex T-Cell Receptor Repertoire Dynamics Underlie the CD8+ T-Cell Response to HIV-1. J. Virol., 89(1):110-119, Jan 2015. PubMed ID: 25320304. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health