HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 59433

HXB2 Location  Gag(180-188)   Gag Epitope Map
View variants at this location
Epitope TPQDLNTML   Epitope Alignment
TPtDLNTML   escape documented in this paper; observed variant
Epitope Name Gag-TL9
Species (MHC/HLA human(B*42:01)

Variant Details

Showing all: 1 variant(s).

Variant ID.  3482
Epitope Seq.  TPQDLNTML
Variant Seq.  TPtDLNTML
Mutations Q/T
Epitope Location Q3T
HXB2 Location Q50T
Mutation Type E: escape documented in this paper
OV: observed variant
Epitope Subtype C
Variant Subtype C
Method Other, Tetramer binding
Note 9% of B*4201+ and 1% of B*4201- subjects (n=1857) carried this escape variant, TPtDLNTML.


Kloverpris2015 Henrik N Kløverpris, Reuben McGregor, James E. McLaren, Kristin Ladell, Mikkel Harndahl, Anette Stryhn, Jonathan M. Carlson, Catherine Koofhethile, Bram Gerritsen, Can Keşmir, Fabian Chen, Lynn Riddell, Graz Luzzi, Alasdair Leslie, Bruce D. Walker, Thumbi Ndung'u, Søren Buus, David A. Price, and Philip J. Goulder. CD8+ TCR Bias and Immunodominance in HIV-1 Infection. J. Immunol., 194(11):5329-5345, 1 Jun 2015. PubMed ID: 25911754. Show all entries for this paper.

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