HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||Gag(162-172)|| Gag Epitope Map
View variants at this location
|Species (MHC/HLA)||human(B*57:01, B*57:03)|
Showing 1 of 8 variants.
|Mutation Type||SSF: subtype-specific susceptible form|
|Method||CD8 T-cell Elispot - IFNy, Chromium-release assay, Tetramer binding|
|Note||Variant found in clade A. It was recognized by CTLs and induced lysis of peptide-pulsed targets. The variant induced IFN-gamma secretion in PBMCs from 5 patients and did not induce secretion in PBMCs from 1 patient.|
Gillespie2002 Geraldine M. A. Gillespie, Rupert Kaul, Tao Dong, Hong-Bing Yang, Tim Rostron, Job J. Bwayo, Peter Kiama, Tim Peto, Francis A. Plummer, Andrew J. McMichael, and Sarah L. Rowland-Jones. Cross-Reactive Cytotoxic T Lymphocytes against a HIV-1 P24 Epitope in Slow Progressors with B*57. AIDS, 16(7):961-972, 3 May 2002. PubMed ID: 11953462. Show all entries for this paper.