HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(151-159) | Gag Epitope Map
View variants at this location |
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| Epitope |
TLNAWVKVV
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Epitope Alignment | ||||
| Variants |
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| Species (MHC/HLA) | human(A*02:01) | |||||
Showing 1 of 4 variants.
| Variant ID. | 3380 |
|---|---|
| Epitope Seq. | TLNAWVKVV |
| Variant Seq. | PLNAWVKVV |
| Mutations | T/P |
| Epitope Location | T1P |
| HXB2 Location | T151P |
| Mutation Type | SF: susceptible form |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | CD8 T-cell Elispot - IFNy, Sequence |
| Note | Third variant to arise; seen in early and late ART periods; positive Elispot >600 SFC/106PBMC in early ART, and 100-200 SFC/106PBMC in late ART period. |
Melhem2014 Nada M Melhem, Kellie N. Smith, Xiao-Li Huang, Bonnie A Colleton, Weimin Jiang, Robbie B. Mailliard, James I. Mullins, and Charles R. Rinaldo. The Impact of Viral Evolution and Frequency of Variant Epitopes on Primary and Memory Human Immunodeficiency Virus Type 1-Specific CD8+ T Cell Responses. Virology, 450-451:34-48, Feb 2014. PubMed ID: 24503065. Show all entries for this paper.