HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 59230

HXB2 Location  Gag(148-156)   Gag Epitope Map
View variants at this location
Epitope SPRTLNAWV   Epitope Alignment
SPRALNAWV   susceptible form
Species (MHC/HLA human(B*07:02)

Variant Details

Showing 1 of 5 variants.

Variant ID.  3374
Epitope Seq.  SPRTLNAWV
Variant Seq.  SPRALNAWV
Mutations T/A
Epitope Location T4A
HXB2 Location T151A
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Sequence
Note Second variant to arise; seen in early post-seroconversion period; positive Elispot response <100 SFC/106PBMC.


Melhem2014 Nada M Melhem, Kellie N. Smith, Xiao-Li Huang, Bonnie A Colleton, Weimin Jiang, Robbie B. Mailliard, James I. Mullins, and Charles R. Rinaldo. The Impact of Viral Evolution and Frequency of Variant Epitopes on Primary and Memory Human Immunodeficiency Virus Type 1-Specific CD8+ T Cell Responses. Virology, 450-451:34-48, Feb 2014. PubMed ID: 24503065. Show all entries for this paper.

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