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Found 1 matching record:

Displaying record number 59208

HXB2 Location  Gag(162-172)   Gag Epitope Map
View variants at this location
Epitope KAFSPEVIPMF   Epitope Alignment
Variants
KAFSPEVIPMt   observed variant
Epitope Name KF11
Species (MHC/HLA human(B*57:01)

Variant Details

Showing 1 of 4 variants.


Variant ID.  3345
Epitope Seq.  KAFSPEVIPMF
Variant Seq.  KAFSPEVIPMt
Mutations F/T
Epitope Location F11T
HXB2 Location F172T
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method HLA binding, Intracellular cytokine staining, Sequence
Note Variant KAFSPEVIPMt was seen in 1/3 HRP (patient P1) and 1/3 LRP (patient P6) subjects.

References

Buggert2014 Marcus Buggert, Melissa M. Norström, Marco Salemi, Frederick M. Hecht, and Annika C. Karlsson. Functional Avidity and IL-2/Perforin Production Is Linked to the Emergence of Mutations within HLA-B*5701-Restricted Epitopes and HIV-1 Disease Progression. J. Immunol., 192(10):4685-4696, 15 May 2014. PubMed ID: 24740510. Show all entries for this paper.


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