Search the Epitope Variant and Escape Mutation Database

Help

Found 1 matching record:

Displaying record number 59207

HXB2 Location Gag(147-155) Gag Epitope Map
View variants at this location

Epitope

ISPRTLNAW

Epitope Alignment

Variants

ltPRTLNAW observed variant

Epitope Name ISW9

Species (MHC/HLA) human(B*57:01)

Variant Details

Showing 1 of 5 variants.

Variant ID.	`3340`
Epitope Seq.	`ISPRTLNAW`
Variant Seq.	`ltPRTLNAW`
Mutations	I/L S/T
Epitope Location	I1L S2T
HXB2 Location	I147L S148T
Mutation Type	OV: observed variant
Epitope Subtype	B
Variant Subtype	B
Method	HLA binding, Intracellular cytokine staining, Sequence
Note	Variant ltPRTLNAW, was seen in 0/3 HRPs and 1/3 LRPs (patient P4) at the last sampling point.

References

Buggert2014 Marcus Buggert, Melissa M. Norström, Marco Salemi, Frederick M. Hecht, and Annika C. Karlsson. Functional Avidity and IL-2/Perforin Production Is Linked to the Emergence of Mutations within HLA-B*5701-Restricted Epitopes and HIV-1 Disease Progression. J. Immunol., 192(10):4685-4696, 15 May 2014. PubMed ID: 24740510. Show all entries for this paper.