HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 59207

HXB2 Location  Gag(147-155)   Gag Epitope Map
View variants at this location
Epitope ISPRTLNAW   Epitope Alignment
Variants
ltPRTLNAW   observed variant
Epitope Name ISW9
Species (MHC/HLA human(B*57:01)

Variant Details

Showing 1 of 5 variants.


Variant ID.  3340
Epitope Seq.  ISPRTLNAW
Variant Seq.  ltPRTLNAW
Mutations I/L S/T
Epitope Location I1L S2T
HXB2 Location I147L S148T
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method HLA binding, Intracellular cytokine staining, Sequence
Note Variant ltPRTLNAW, was seen in 0/3 HRPs and 1/3 LRPs (patient P4) at the last sampling point.

References

Buggert2014 Marcus Buggert, Melissa M. Norström, Marco Salemi, Frederick M. Hecht, and Annika C. Karlsson. Functional Avidity and IL-2/Perforin Production Is Linked to the Emergence of Mutations within HLA-B*5701-Restricted Epitopes and HIV-1 Disease Progression. J. Immunol., 192(10):4685-4696, 15 May 2014. PubMed ID: 24740510. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health