HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 59019

HXB2 Location  Gag(168-185)   Gag Epitope Map
View variants at this location
Epitope VIPMFSALSEGATPQDLN   Epitope Alignment
VIPMFtALSEGATPQDLN   subtype-specific susceptible form
Epitope Name CE2
Species (MHC/HLA mouse

Variant Details

Showing all: 1 variant(s).

Variant ID.  3206
Mutations S/T
Epitope Location S6T
HXB2 Location S173T
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype A, B, M group
Variant Subtype C
Method Intracellular cytokine staining
Note VIPMFtALSEGATPQDLN is the Clade-C variant of CE2. It was used in the p24CE2 vaccine form in this study, eliciting a robust CTL response from the vaccinated mouse.


Kulkarni2013 Viraj Kulkarni, Margherita Rosati, Antonio Valentin, Brunda Ganneru, Ashish K. Singh, Jian Yan, Morgane Rolland, Candido Alicea, Rachel Kelly Beach, Gen-Mu Zhang, Sylvie Le Gall, Kate E. Broderick, Niranjan Y. Sardesai, David Heckerman, Beatriz Mothe, Christian Brander, David B. Weiner, James I. Mullins, George N. Pavlakis, and Barbara K. Felber. HIV-1 p24(gag) Derived Conserved Element DNA Vaccine Increases the Breadth of Immune Response in Mice. PLoS One, 8(3):e60245, 2013. PubMed ID: 23555935. Show all entries for this paper.

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