HIV molecular immunology database

 

Search the Epitope Variant and Escape Mutation Database

Help


Found 1 matching record:

Displaying record number 59019

HXB2 Location  Gag(168-185)   Gag Epitope Map
View variants at this location
Epitope VIPMFSALSEGATPQDLN   Epitope Alignment
Variants
VIPMFtALSEGATPQDLN   subtype-specific susceptible form
Epitope Name CE2
Species (MHC/HLA mouse

Variant Details

Showing all: 1 variant(s).


Variant ID.  3206
Epitope Seq.  VIPMFSALSEGATPQDLN
Variant Seq.  VIPMFtALSEGATPQDLN
Mutations S/T
Epitope Location S6T
HXB2 Location S173T
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype A, B, M group
Variant Subtype C
Method Intracellular cytokine staining
Note VIPMFtALSEGATPQDLN is the Clade-C variant of CE2. It was used in the p24CE2 vaccine form in this study, eliciting a robust CTL response from the vaccinated mouse.

References

Kulkarni2013 Viraj Kulkarni, Margherita Rosati, Antonio Valentin, Brunda Ganneru, Ashish K. Singh, Jian Yan, Morgane Rolland, Candido Alicea, Rachel Kelly Beach, Gen-Mu Zhang, Sylvie Le Gall, Kate E. Broderick, Niranjan Y. Sardesai, David Heckerman, Beatriz Mothe, Christian Brander, David B. Weiner, James I. Mullins, George N. Pavlakis, and Barbara K. Felber. HIV-1 p24(gag) Derived Conserved Element DNA Vaccine Increases the Breadth of Immune Response in Mice. PLoS One, 8(3):e60245, 2013. PubMed ID: 23555935. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health