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HIV Molecular Immunology Database

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Found 1 matching record:

Displaying record number 59021

HXB2 Location  Gag(231-249)   Gag Epitope Map
View variants at this location
Epitope PRGSDIAGTTSTLQEQIGW   Epitope Alignment
Variants
PRGSDIAGTTSTLQEQIaW   subtype-specific susceptible form
Epitope Name CE4
Species (MHC/HLA mouse

Variant Details

Showing 1 of 2 variants.


Variant ID.  3204
Epitope Seq.  PRGSDIAGTTSTLQEQIGW
Variant Seq.  PRGSDIAGTTSTLQEQIaW
Mutations G/A
Epitope Location G18A
HXB2 Location G248A
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C, M group
Method Intracellular cytokine staining
Note PRGSDIAGTTSTLQEQIaW is the Clades-C and -M variant of CE4. It was used in the p24CE2 vaccine form in this study, eliciting no response.

References

Kulkarni2013 Viraj Kulkarni, Margherita Rosati, Antonio Valentin, Brunda Ganneru, Ashish K. Singh, Jian Yan, Morgane Rolland, Candido Alicea, Rachel Kelly Beach, Gen-Mu Zhang, Sylvie Le Gall, Kate E. Broderick, Niranjan Y. Sardesai, David Heckerman, Beatriz Mothe, Christian Brander, David B. Weiner, James I. Mullins, George N. Pavlakis, and Barbara K. Felber. HIV-1 p24(gag) Derived Conserved Element DNA Vaccine Increases the Breadth of Immune Response in Mice. PLoS One, 8(3):e60245, 2013. PubMed ID: 23555935. Show all entries for this paper.


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