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Displaying record number 53202

HXB2 Location Gag(20-28) Gag Epitope Map
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Epitope

RLRPGGKKK

Epitope Alignment

Variants

RLRPGGKqK escape documented in this paper

Epitope Name RK9

Species (MHC/HLA) human(A3)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`32`
Epitope Seq.	`RLRPGGKKK`
Variant Seq.	`RLRPGGKqK`
Mutations	K/Q
Epitope Location	K8Q
HXB2 Location	K27Q
Mutation Type	E: escape documented in this paper
Method	CD8 T-cell Elispot - IFNy, Flow cytometric T-cell cytokine assay
Note	Variant abrogates the response.

References

Allen2004 Todd M Allen, Marcus Altfeld, Xu G. Yu, Kristin M. O'Sullivan, Mathias Lichterfeld, Sylvie Le Gall, Mina John, Bianca R. Mothe, Paul K. Lee, Elizabeth T. Kalife, Daniel E. Cohen, Kenneth A. Freedberg, Daryld A. Strick, Mary N. Johnston, Alessandro Sette, Eric S. Rosenberg, Simon A. Mallal, Philip J. R. Goulder, Christian Brander, and Bruce D. Walker. Selection, Transmission, and Reversion of an Antigen-Processing Cytotoxic T-Lymphocyte Escape Mutation in Human Immunodeficiency Virus Type 1 Infection. J. Virol., 78(13):7069-7078, Jul 2004. PubMed ID: 15194783. Show all entries for this paper.