HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 53202

HXB2 Location  Gag(20-28)   Gag Epitope Map
View variants at this location
Epitope RLRPGGKKK   Epitope Alignment
RLRPGGKqK   escape documented in this paper
Epitope Name RK9
Species (MHC/HLA human(A3)

Variant Details

Showing all: 1 variant(s).

Variant ID.  32
Epitope Seq.  RLRPGGKKK
Variant Seq.  RLRPGGKqK
Mutations K/Q
Epitope Location K8Q
HXB2 Location K27Q
Mutation Type E: escape documented in this paper
Method CD8 T-cell Elispot - IFNy, Flow cytometric T-cell cytokine assay
Note Variant abrogates the response.


Allen2004 Todd M Allen, Marcus Altfeld, Xu G. Yu, Kristin M. O'Sullivan, Mathias Lichterfeld, Sylvie Le Gall, Mina John, Bianca R. Mothe, Paul K. Lee, Elizabeth T. Kalife, Daniel E. Cohen, Kenneth A. Freedberg, Daryld A. Strick, Mary N. Johnston, Alessandro Sette, Eric S. Rosenberg, Simon A. Mallal, Philip J. R. Goulder, Christian Brander, and Bruce D. Walker. Selection, Transmission, and Reversion of an Antigen-Processing Cytotoxic T-Lymphocyte Escape Mutation in Human Immunodeficiency Virus Type 1 Infection. J. Virol., 78(13):7069-7078, Jul 2004. PubMed ID: 15194783. Show all entries for this paper.

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