HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 58840

HXB2 Location  Gag(162-172)   Gag Epitope Map
View variants at this location
Epitope KAFSPEVIPMF   Epitope Alignment
KAFSPEiIPMF   observed variant
Epitope Name KF11
Species (MHC/HLA human(B*57:01)

Variant Details

Showing 1 of 4 variants.

Variant ID.  3183
Variant Seq.  KAFSPEiIPMF
Mutations V/I
Epitope Location V7I
HXB2 Location V167I
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Flow cytometric T-cell cytokine assay
Note Epitope mutation, E|KAFSPEiIPMF|S, was seen for KF11 by 168 weeks post-infection in P1 who carried HLA alleles A*0101,A*0301,B*2705,B*5701 and by 301 weeks post-infection in P6 who carried HLA alleles A*0301,A*2402,B*3501,B*5701.


Norstrom2012 Melissa M. Norström, Marcus Buggert, Johanna Tauriainen, Wendy Hartogensis, Mattia C. Prosperi, Mark A. Wallet, Frederick M. Hecht, Marco Salemi, and Annika C. Karlsson. Combination of Immune and Viral Factors Distinguishes Low-Risk Versus High-Risk HIV-1 Disease Progression in HLA-B*5701 Subjects. J. Virol., 86(18):9802-9816, Sep 2012. PubMed ID: 22761389. Show all entries for this paper.

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