HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 58812

HXB2 Location  Gag(147-155)   Gag Epitope Map
View variants at this location
Epitope ISPRTLNAW   Epitope Alignment
{p}ISPRTLNAW   observed variant
Epitope Name ISW9
Species (MHC/HLA human(B*57:01)

Variant Details

Showing 1 of 9 variants.

Variant ID.  3175
Epitope Seq.  {A}ISPRTLNAW
Variant Seq.  {p}ISPRTLNAW
Mutations A/P
Epitope Location A-1P
HXB2 Location A145P
Mutation Type OV: observed variant
Epitope Subtype B
Variant Subtype B
Method Sequence
Note Flanking mutation, {p}ISPRTLNAW{V}, was seen for ISW9 from 75 weeks post-infection in patient 3 (P3) who carried HLA alleles A*2402 , A*3201, B*4002, B*5701; from 60 weeks post-infection in P4 who carried HLA alleles A*0101,A*0201,B*5101,B*5701; and from 10 weeks post-infection in P6 who carried HLA alleles A*0301,A*2402,B*3501,B*5701.


Norstrom2012 Melissa M. Norström, Marcus Buggert, Johanna Tauriainen, Wendy Hartogensis, Mattia C. Prosperi, Mark A. Wallet, Frederick M. Hecht, Marco Salemi, and Annika C. Karlsson. Combination of Immune and Viral Factors Distinguishes Low-Risk Versus High-Risk HIV-1 Disease Progression in HLA-B*5701 Subjects. J. Virol., 86(18):9802-9816, Sep 2012. PubMed ID: 22761389. Show all entries for this paper.

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