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Displaying record number 58813

HXB2 Location Gag(180-188) Gag Epitope Map
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Epitope

TPQDLNTML

Epitope Alignment

Variants

TPQDLNTMf{...q...v...i} observed variant

Epitope Name TL9

Species (MHC/HLA) human(B*39:10, B*81:01)

Variant Details

Showing 1 of 17 variants.

Variant ID.	`3171`
Epitope Seq.	`TPQDLNTML{...H...I...M}`
Variant Seq.	`TPQDLNTMf{...q...v...i}`
Mutations	H/Q I/V M/I L/F
Epitope Location	H31Q I35V M62I L9F
HXB2 Location	H219Q I223V M250I L188F
Mutation Type	OV: observed variant
Epitope Subtype	C
Variant Subtype	C
Method	Sequence
Note	A mutation within TL9, L188F had developed by 76 weeks post-infection, and putative compensatory mutations H219Q, I223V and M250I had also developed by then in a B4201, Cw0802-positive subject

References

Ntale2012 R. S. Ntale, D. R. Chopera, N. K. Ngandu, D. Assis de Rosa, L. Zembe, H. Gamieldien, M. Mlotshwa, L. Werner, Z. Woodman, K. Mlisana, S. Abdool Karim, C. M. Gray, C. Williamson, and CAPRISA 002 Study Team. Temporal Association of HLA-B*81:01- and HLA-B*39:10-Mediated HIV-1 p24 Sequence Evolution with Disease Progression. J. Virol., 86(22):12013-12024, Nov 2012. PubMed ID: 22933291. Show all entries for this paper.