HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||Gag(180-188)|| Gag Epitope Map
View variants at this location
|Species (MHC/HLA)||human(B*39:10, B*81:01)|
Showing 1 of 17 variants.
|Epitope Location||Q3S M+62I|
|HXB2 Location||Q182S M250I|
|Mutation Type||OV: observed variant|
|Note||A mutation within TL9, Q182S, had developed by 84 weeks post-infection, and a putative compensatory mutation, M250I, had also developed by then in a B*8101-positive subject [Donor HLA = A*3009, A*4301, B*5802, B*8101, Cw*0401, Cw*0401; this subject was a controller for the first 18-24 months and thereafter became a progressor].|
Ntale2012 R. S. Ntale, D. R. Chopera, N. K. Ngandu, D. Assis de Rosa, L. Zembe, H. Gamieldien, M. Mlotshwa, L. Werner, Z. Woodman, K. Mlisana, S. Abdool Karim, C. M. Gray, C. Williamson, and CAPRISA 002 Study Team. Temporal Association of HLA-B*81:01- and HLA-B*39:10-Mediated HIV-1 p24 Sequence Evolution with Disease Progression. J. Virol., 86(22):12013-12024, Nov 2012. PubMed ID: 22933291. Show all entries for this paper.