HIV molecular immunology database
Found 1 matching record:
HXB2 Location | Gag(180-188) | Gag Epitope Map
View variants at this location |
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Epitope |
TPQDLNTML
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Epitope Alignment | ||||
Variants |
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Epitope Name | TL9 | |||||
Species (MHC/HLA) | human(B*39:10, B*81:01) |
Showing 1 of 17 variants.
Variant ID. | 3162 |
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Epitope Seq. | TPQDLNTML{...I...I} |
Variant Seq. | TPaDLNTML{...v...v} |
Mutations | Q/A I/V I/V |
Epitope Location | Q3A I+35V I+68V |
HXB2 Location | Q182A I223V I256V |
Mutation Type | OV: observed variant |
Epitope Subtype | C |
Variant Subtype | C |
Method | Sequence |
Note | A mutation within TL9, Q182A had developed by 8 weeks post-infection, and putative compensatory mutations I223V and !256V had also developed by then in a B*3910-positive subject, weeks post-infection [Donor HLA = A*3001, A*4301, B*3901, B*4202, Cw*1203, Cw*1701; a controller of infection] |
Ntale2012 R. S. Ntale, D. R. Chopera, N. K. Ngandu, D. Assis de Rosa, L. Zembe, H. Gamieldien, M. Mlotshwa, L. Werner, Z. Woodman, K. Mlisana, S. Abdool Karim, C. M. Gray, C. Williamson, and CAPRISA 002 Study Team. Temporal Association of HLA-B*81:01- and HLA-B*39:10-Mediated HIV-1 p24 Sequence Evolution with Disease Progression. J. Virol., 86(22):12013-12024, Nov 2012. PubMed ID: 22933291. Show all entries for this paper.