HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 58813

HXB2 Location  Gag(180-188)   Gag Epitope Map
View variants at this location
Epitope TPQDLNTML   Epitope Alignment
TPsDLNTML{...a...v}   observed variant
Epitope Name TL9
Species (MHC/HLA human(B*39:10, B*81:01)

Variant Details

Showing 1 of 17 variants.

Variant ID.  3158
Epitope Seq.  TPQDLNTML{...I...I}
Variant Seq.  TPsDLNTML{...a...v}
Mutations Q/S I/A I/V
Epitope Location Q3S I+35A I+68V
HXB2 Location Q182S I223A I256V
Mutation Type OV: observed variant
Epitope Subtype C
Variant Subtype C
Method Sequence
Note A mutation within TL9, Q182S, had developed by 83 weeks post-infection, and putative compensatory mutations I223A and I26V had also developed by then in a B*8101-positive subject [Donor HLA = A*3001, A*3303, B*5301, B*8101, Cw*0401, Cw*0401; after an initial 18-24 months of control, this subject had an increased VL and decreased CD4+ T cell counts]


Ntale2012 R. S. Ntale, D. R. Chopera, N. K. Ngandu, D. Assis de Rosa, L. Zembe, H. Gamieldien, M. Mlotshwa, L. Werner, Z. Woodman, K. Mlisana, S. Abdool Karim, C. M. Gray, C. Williamson, and CAPRISA 002 Study Team. Temporal Association of HLA-B*81:01- and HLA-B*39:10-Mediated HIV-1 p24 Sequence Evolution with Disease Progression. J. Virol., 86(22):12013-12024, Nov 2012. PubMed ID: 22933291. Show all entries for this paper.

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