HIV molecular immunology database
Found 1 matching record:
|HXB2 Location||Gag(180-188)|| Gag Epitope Map
View variants at this location
|Species (MHC/HLA)||human(B*39:10, B*81:01)|
Showing 1 of 17 variants.
|Mutations||Q/S I/A I/V|
|Epitope Location||Q3S I+35A I+68V|
|HXB2 Location||Q182S I223A I256V|
|Mutation Type||OV: observed variant|
|Note||A mutation within TL9, Q182S, had developed by 83 weeks post-infection, and putative compensatory mutations I223A and I26V had also developed by then in a B*8101-positive subject [Donor HLA = A*3001, A*3303, B*5301, B*8101, Cw*0401, Cw*0401; after an initial 18-24 months of control, this subject had an increased VL and decreased CD4+ T cell counts]|
Ntale2012 R. S. Ntale, D. R. Chopera, N. K. Ngandu, D. Assis de Rosa, L. Zembe, H. Gamieldien, M. Mlotshwa, L. Werner, Z. Woodman, K. Mlisana, S. Abdool Karim, C. M. Gray, C. Williamson, and CAPRISA 002 Study Team. Temporal Association of HLA-B*81:01- and HLA-B*39:10-Mediated HIV-1 p24 Sequence Evolution with Disease Progression. J. Virol., 86(22):12013-12024, Nov 2012. PubMed ID: 22933291. Show all entries for this paper.