HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(209-218) | Gag Epitope Map
View variants at this location |
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| Epitope |
AAEWDRLHPV
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | p24Gag209-218 | |||||
| Species (MHC/HLA) | human | |||||
Showing 1 of 9 variants.
| Variant ID. | 3151 |
|---|---|
| Epitope Seq. | AAEWDRLHPV |
| Variant Seq. | AAEWDRvHPV |
| Mutations | L/V |
| Epitope Location | L7V |
| HXB2 Location | L215V |
| Mutation Type | A: HLA association |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | HLA binding |
| Note | Gag209-218-V, AAEWDRvHPV, showed a significant increase in binding to HLA-Cw*0102. 16.3% of sequences carried this variant. |
Fadda2012 Lena Fadda, Christian Körner, Swati Kumar, Nienke H. van Teijlingen, Alicja Piechocka-Trocha, Mary Carrington, and Marcus Altfeld. HLA-Cw*0102-Restricted HIV-1 p24 Epitope Variants Can Modulate the Binding of the Inhibitory KIR2DL2 Receptor and Primary NK Cell Function. PLoS Pathog., 8(7):e1002805, 2012. PubMed ID: 22807681. Show all entries for this paper.