HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 58783

HXB2 Location  Gag(209-218)   Gag Epitope Map
View variants at this location
Epitope AAEWDRLHPV   Epitope Alignment
AAEWDRtHPV   HLA association
Epitope Name p24Gag209-218
Species (MHC/HLA human

Variant Details

Showing 1 of 9 variants.

Variant ID.  3150
Epitope Seq.  AAEWDRLHPV
Variant Seq.  AAEWDRtHPV
Mutations L/T
Epitope Location L7T
HXB2 Location L215T
Mutation Type A: HLA association
Epitope Subtype B
Variant Subtype B
Method HLA binding
Note Gag209-218-T, AAEWDRtHPV, showed a significant increase in binding to HLA-Cw*0102. 5.2% of sequences carried this variant.


Fadda2012 Lena Fadda, Christian Körner, Swati Kumar, Nienke H. van Teijlingen, Alicja Piechocka-Trocha, Mary Carrington, and Marcus Altfeld. HLA-Cw*0102-Restricted HIV-1 p24 Epitope Variants Can Modulate the Binding of the Inhibitory KIR2DL2 Receptor and Primary NK Cell Function. PLoS Pathog., 8(7):e1002805, 2012. PubMed ID: 22807681. Show all entries for this paper.

Questions or comments? Contact us at
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health