HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 58700

HXB2 Location  Gag(22-30)   Gag Epitope Map
View variants at this location
Epitope RPGGKKHYM   Epitope Alignment
RPGGKKHYr   observed variant
Epitope Name p17-RM9
Species (MHC/HLA human(B*42:01, B*42:02)

Variant Details

Showing 1 of 3 variants.

Variant ID.  3112
Epitope Seq.  RPGGKKHYM
Variant Seq.  RPGGKKHYr
Mutations M/R
Epitope Location M9R
HXB2 Location M30R
Mutation Type OV: observed variant
Epitope Subtype C
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, HLA binding, Sequence
Note p17-RM9 mutation, RPGGKKHYr, is selected in 4% HLA-B*4201 (8% have wt RM9), 0% HLA-B*4202 (31% have wt RM9) and 1% on-HLA-B*42 (46% have wt RM9) subjects.


Kloverpris2012a Henrik N. Kløverpris, Mikkel Harndahl, Alasdair J. Leslie, Jonathan M. Carlson, Nasreen Ismail, Mary van der Stok, Kuan-Hsiang Gary Huang, Fabian Chen, Lynn Riddell, Dewald Steyn, Dominique Goedhals, Cloete van Vuuren, John Frater, Bruce D. Walker, Mary Carrington, Thumbi Ndung'u, Søren Buus, and Philip Goulder. HIV Control through a Single Nucleotide on the HLA-B Locus. J. Virol., 86(21):11493-11500, Nov 2012. PubMed ID: 22896606. Show all entries for this paper.

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