HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(22-30) | Gag Epitope Map
View variants at this location |
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| Epitope |
RPGGKKHYM
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | p17-RM9 | |||||
| Species (MHC/HLA) | human(B*42:01, B*42:02) | |||||
Showing 1 of 3 variants.
| Variant ID. | 3112 |
|---|---|
| Epitope Seq. | RPGGKKHYM |
| Variant Seq. | RPGGKKHYr |
| Mutations | M/R |
| Epitope Location | M9R |
| HXB2 Location | M30R |
| Mutation Type | OV: observed variant |
| Epitope Subtype | C |
| Variant Subtype | C |
| Method | CD8 T-cell Elispot - IFNy, HLA binding, Sequence |
| Note | p17-RM9 mutation, RPGGKKHYr, is selected in 4% HLA-B*4201 (8% have wt RM9), 0% HLA-B*4202 (31% have wt RM9) and 1% on-HLA-B*42 (46% have wt RM9) subjects. |
Kloverpris2012a Henrik N. Kløverpris, Mikkel Harndahl, Alasdair J. Leslie, Jonathan M. Carlson, Nasreen Ismail, Mary van der Stok, Kuan-Hsiang Gary Huang, Fabian Chen, Lynn Riddell, Dewald Steyn, Dominique Goedhals, Cloete van Vuuren, John Frater, Bruce D. Walker, Mary Carrington, Thumbi Ndung'u, Søren Buus, and Philip Goulder. HIV Control through a Single Nucleotide on the HLA-B Locus. J. Virol., 86(21):11493-11500, Nov 2012. PubMed ID: 22896606. Show all entries for this paper.