HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


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Displaying record number 58604

HXB2 Location  Gag(76-86)   Gag Epitope Map
View variants at this location
Epitope RSLYNTVATLY   Epitope Alignment
RSLYNTVATLc   escape documented in this paper
Epitope Name GagRY11
Species (MHC/HLA human, macaque(A*30:02)

Variant Details

Showing 1 of 3 variants.

Variant ID.  3056
Variant Seq.  RSLYNTVATLc
Mutations Y/C
Epitope Location Y11C
HXB2 Location Y86C
Mutation Type E: escape documented in this paper
Method Cytokine production, Sequence, Tetramer binding
Note 5/5 (100%) sequenced variants showed this escape, RSLYNTVATLc, in subject 0406; 13/15 (86.7%) in subject 2401; and 8/16 (50%) in subject 3902.


Mahlokozera2011 Tatenda Mahlokozera, Helen H. Kang, Nilu Goonetilleke, Andrea R. Stacey, Rachel V. Lovingood, Thomas N. Denny, Linda Kalilani, James E. G. Bunn, Steve R. Meshnick, Persephone Borrow, Norman L. Letvin, Sallie R. Permar, and Center for HIV/AIDS Vaccine Immunology. The Magnitude and Kinetics of the Mucosal HIV-Specific CD8+ T Lymphocyte Response and Virus RNA Load in Breast Milk. PLoS One, 6(8):e23735, 2011. PubMed ID: 21886819. Show all entries for this paper.

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