HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 58386

HXB2 Location  Gag(129-143)   Gag Epitope Map
View variants at this location
Epitope SQNYPIVQNLQGQMV   Epitope Alignment
kvSQNYalkhrayel   subtype-specific non-susceptible form
Epitope Name Peptide 32
Species (MHC/HLA human

Variant Details

Showing 1 of 2 variants.

Variant ID.  2916
Variant Seq.  kvSQNYalkhrayel
Mutations x/K Q/H N/R L/A Q/Y G/E M/L x/V P/A I/L V/K
Epitope Location x1K Q10H N11R L12A Q13Y G14E M15L x2V P7A I8L V9K
HXB2 Location x129K Q138H N139R L140A Q141Y G142E M143L x130V P135A I136L V137K
Mutation Type SNSF: subtype-specific non-susceptible form
Epitope Subtype C
Variant Subtype A
Method CD8 T-cell Elispot - IFNy, Sequence
Note Consensus Clade-A peptide 32, kvSQNYalkhrayel, did not elicit a response from South African subjects carrying clade-C virus.


Zembe2011 Lycias Zembe, Wendy A. Burgers, Heather B. Jaspan, Linda-Gail Bekker, Helba Bredell, Gwynneth Stevens, Jill Gilmour, Josephine H. Cox, Patricia Fast, Peter Hayes, Eftyhia Vardas, Carolyn Williamson, and Clive M. Gray. Intra- and Inter-Clade Cross-Reactivity by HIV-1 Gag Specific T-Cells Reveals Exclusive and Commonly Targeted Regions: Implications for Current Vaccine Trials. PLoS One, 6(10):e26096, 2011. PubMed ID: 22022524. Show all entries for this paper.

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