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Displaying record number 58244

HXB2 Location Gag(20-28) Gag Epitope Map
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Epitope

RLRPGGKKK

Epitope Alignment

Variants

{rWEKI}RLRPGGKKK inferred escape

Species (MHC/HLA) human(A*03:01)

Variant Details

Showing all: 1 variant(s).

Variant ID.	`2835`
Epitope Seq.	`{KWEKI}RLRPGGKKK`
Variant Seq.	`{rWEKI}RLRPGGKKK`
Mutations	K/R
Epitope Location	K-5R
HXB2 Location	K15R
Mutation Type	IE: inferred escape
Epitope Subtype	B
Variant Subtype	B
Method	Sequence
Note	3/16 and 1/11 sequences of peptide {KWEKI}RLRPGGKKK varied at 639 and 821 DFOSx to {rWEKI}RLRPGGKKK. Position 15 in the peptide is marked as being under selection to vary.

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.