HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(147-155) | Gag Epitope Map
View variants at this location |
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|---|---|---|---|---|---|---|
| Epitope |
ISPRTLNAW
|
Epitope Alignment | ||||
| Variants |
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| Species (MHC/HLA) | human(B*57:01) | |||||
Showing 1 of 2 variants.
| Variant ID. | 2799 |
|---|---|
| Epitope Seq. | ISPRTLNAW |
| Variant Seq. | lSPRTLNAW |
| Mutations | I/L |
| Epitope Location | I1L |
| HXB2 Location | I147L |
| Mutation Type | IE: inferred escape |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | Sequence |
| Note | 1/3 or 2/3 sequences of epitope ISPRTLNAW varied at 350 DFOSx to lSPRTLNAW and xSPRTLNAW, where X = l or s. Position 15 in the epitope is marked as being under selection to vary. |
Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.