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Found 1 matching record:

Displaying record number 58160

HXB2 Location  Gag(145-155)   Gag Epitope Map
View variants at this location
Epitope QAISPRTLNAW   Epitope Alignment
Variants
QAlSPRTLNAW   susceptible form
Epitope Name QW11
Species (MHC/HLA human(A*25:01)

Variant Details

Showing all: 1 variant(s).


Variant ID.  2747
Epitope Seq.  QAISPRTLNAW
Variant Seq.  QAlSPRTLNAW
Mutations I/L
Epitope Location I3L
HXB2 Location I147L
Mutation Type SF: susceptible form
Epitope Subtype B
Variant Subtype B
Method CD8 T-cell Elispot - IFNy, Longitudinal study
Note Major variant QAlSPRTLNAW replaced the wild type sequence by 800 days post-infection. It did not abrogate EliSpot response to the epitope.

References

Liu2011a Yi Liu, John P. McNevin, Sarah Holte, M. Juliana McElrath, and James I. Mullins. Dynamics of Viral Evolution and CTL Responses in HIV-1 Infection. PLoS One, 6(1):e15639, 2011. PubMed ID: 21283794. Show all entries for this paper.


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