HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 58010

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
SLfNTiATL   HLA association; processing
Epitope Name SL9
Species (MHC/HLA human(A*02)

Variant Details

Showing 1 of 5 variants.

Variant ID.  2709
Epitope Seq.  SLYNTVATL
Variant Seq.  SLfNTiATL
Mutations Y/F V/I
Epitope Location Y3F V6I
HXB2 Location Y79F V82I
Mutation Type A: HLA association
P: processing
Epitope Subtype B
Variant Subtype B
Note A2-SL9 has known HLA-associated mutants (T8V, Y3F, V6I, V6I/T8V, Y3F/V6I). All 5 mutants displayed severely reduced half-lives.


Lazaro2011 Estibaliz Lazaro, Carl Kadie, Pamela Stamegna, Shao Chong Zhang, Pauline Gourdain, Nicole Y. Lai, Mei Zhang, Sergio A. Martinez, David Heckerman, and Sylvie Le Gall. Variable HIV Peptide Stability in Human Cytosol Is Critical to Epitope Presentation and Immune Escape. J. Clin. Invest., 121(6):2480-2492, Jun 2011. PubMed ID: 21555856. Show all entries for this paper.

Questions or comments? Contact us at
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health