HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 57682

HXB2 Location  Gag(20-29)   Gag Epitope Map
View variants at this location
Epitope RLRPGGKKKY   Epitope Alignment
qLRPGGKKrY   susceptible form; subtype-specific susceptible form
Epitope Name EnvRY10
Species (MHC/HLA human(A3)

Variant Details

Showing 1 of 4 variants.

Variant ID.  2681
Epitope Seq.  RLRPGGKKKY
Variant Seq.  qLRPGGKKrY
Mutations R/Q K/R
Epitope Location R1Q K9R
HXB2 Location R20Q K28R
Mutation Type SF: susceptible form
SSF: subtype-specific susceptible form
Epitope Subtype A, B, C, D
Variant Subtype D
Method CD8 T-cell Elispot - IFNy, Intracellular cytokine staining
Note Variant qLRPGGKKrY was found at a frequency of 23 in clade D.


Koup2010 Richard A. Koup, Mario Roederer, Laurie Lamoreaux, Jennifer Fischer, Laura Novik, Martha C. Nason, Brenda D. Larkin, Mary E. Enama, Julie E. Ledgerwood, Robert T. Bailer, John R. Mascola, Gary J. Nabel, Barney S. Graham, VRC 009 Study Team, and VRC 010 Study Team. Priming Immunization with DNA Augments Immunogenicity of Recombinant Adenoviral Vectors for Both HIV-1 Specific Antibody and T-Cell Responses. PLoS One, 5(2):e9015, 2010. PubMed ID: 20126394. Show all entries for this paper.

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