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Displaying record number 57682

HXB2 Location Gag(20-29) Gag Epitope Map
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Epitope

RLRPGGKKKY

Epitope Alignment

Variants

RLRPGGKKrY susceptible form; subtype-specific susceptible form

Epitope Name EnvRY10

Species (MHC/HLA) human(A3)

Variant Details

Showing 1 of 4 variants.

Variant ID.	`2679`
Epitope Seq.	`RLRPGGKKKY`
Variant Seq.	`RLRPGGKKrY`
Mutations	K/R
Epitope Location	K9R
HXB2 Location	K28R
Mutation Type	SF: susceptible form SSF: subtype-specific susceptible form
Epitope Subtype	A, B, C, D
Variant Subtype	B, C
Method	CD8 T-cell Elispot - IFNy, Intracellular cytokine staining
Note	Variant RLRPGGKKrY was found at frequencies of 9 and 14 in clades B and C respectively.

References

Koup2010 Richard A. Koup, Mario Roederer, Laurie Lamoreaux, Jennifer Fischer, Laura Novik, Martha C. Nason, Brenda D. Larkin, Mary E. Enama, Julie E. Ledgerwood, Robert T. Bailer, John R. Mascola, Gary J. Nabel, Barney S. Graham, VRC 009 Study Team, and VRC 010 Study Team. Priming Immunization with DNA Augments Immunogenicity of Recombinant Adenoviral Vectors for Both HIV-1 Specific Antibody and T-Cell Responses. PLoS One, 5(2):e9015, 2010. PubMed ID: 20126394. Show all entries for this paper.