Found 1 matching record:
HXB2 Location | Env(172-188) | Env Epitope Map
View variants at this location |
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Epitope |
VHALFYKLDIVPIEDNK
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Epitope Alignment | ||||
Variants |
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Epitope Name | peptide 32, pep 32 | |||||
Species (MHC/HLA) | human |
Showing 1 of 9 variants.
Variant ID. | 26 |
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Epitope Seq. | VHALFYKLDIVPIEDNK |
Variant Seq. | VHALFYKLDlVqIEDNK |
Mutations | I/L P/Q |
Epitope Location | I10L P12Q |
HXB2 Location | I181L P183Q |
Mutation Type | E: escape documented in this paper NSF: non-susceptible form |
Epitope Subtype | B, CRF01_AE |
Variant Subtype | B, CRF01_AE |
Method | CD8 T-cell Elispot - IFNy |
Note | Peptide 32 variant VHALFYKLDlVqIEDNK, completely abrogated CTL response in all 4 previously vaccinated subjects from RV144 that were tested. |
Ratto-Kim2015 Silvia Ratto-Kim, Mark S. de Souza, Jeffrey R. Currier, Nicos Karasavvas, John Sidney, Morgane Rolland, Anais Valencia-Micolta, Sirinan Madnote, Alessandro Sette, Sorachai Nitayaphan, Punnee Pitisuttuthum, Jaranit Kaewkungwal, Supachai Rerks-Ngarm, Robert O'Connell, Nelson Michael, Merlin L. Robb, Mary Marovich, and Jerome H. Kim. Identification of Immunodominant CD4-Restricted Epitopes Co-Located with Antibody Binding Sites in Individuals Vaccinated with ALVAC-HIV and AIDSVAX B/E. PLoS One, 10(2):e0115582, 2015. PubMed ID: 25665096. Show all entries for this paper.
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