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Displaying record number 57652

HXB2 Location Gag(164-172) Gag Epitope Map
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Epitope

FSPEVIPMF

Epitope Alignment

Variants

FnPEiIPMF susceptible form

Species (MHC/HLA) macaque(Mamu-A*01)

Variant Details

Showing 1 of 6 variants.

Variant ID.	`2575`
Epitope Seq.	`FSPEVIPMF`
Variant Seq.	`FnPEiIPMF`
Mutations	S/N V/I
Epitope Location	S2N V5I
HXB2 Location	S165N V168I
Mutation Type	SF: susceptible form
Method	CD8 T-cell Elispot - IFNy
Note	T cells specific for FSPEVIPMF recognized equally strongly all tested epitope variants: FnPEVIPMF, FSPEiIPMF, qSPEVIPMF, FnPEiIPMF, FSPqVIPMF in rhesus macaques vaccinated with HIVconsv.

References

Rosario2010 Maximillian Rosario, Anne Bridgeman, Esther D. Quakkelaar, Maire F. Quigley, Brenna J. Hill, Maria L. Knudsen, Virginia Ammendola, Karl Ljungberg, Nicola Borthwick, Eung-Jun Im, Andrew J. McMichael, Jan W. Drijfhout, Hui Yee Greenaway, Vanessa Venturi, Daniel C. Douek, Stefano Colloca, Peter Liljeström, Alfredo Nicosia, David A. Price, Cornelis J. M. Melief, and Tomáš Hanke. Long Peptides Induce Polyfunctional T Cells against Conserved Regions of HIV-1 with Superior Breadth to Single-Gene Vaccines in Macaques. Eur. J. Immunol., 40(7):1973-1984, Jul 2010. PubMed ID: 20468055. Show all entries for this paper.