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Found 1 matching record:

Displaying record number 57652

HXB2 Location  Gag(164-172)   Gag Epitope Map
View variants at this location
Epitope FSPEVIPMF   Epitope Alignment
Variants
FnPEiIPMF   susceptible form
Species (MHC/HLA macaque(Mamu-A*01)

Variant Details

Showing 1 of 6 variants.


Variant ID.  2575
Epitope Seq.  FSPEVIPMF
Variant Seq.  FnPEiIPMF
Mutations S/N V/I
Epitope Location S2N V5I
HXB2 Location S165N V168I
Mutation Type SF: susceptible form
Method CD8 T-cell Elispot - IFNy
Note T cells specific for FSPEVIPMF recognized equally strongly all tested epitope variants: FnPEVIPMF, FSPEiIPMF, qSPEVIPMF, FnPEiIPMF, FSPqVIPMF in rhesus macaques vaccinated with HIVconsv.

References

Rosario2010 Maximillian Rosario, Anne Bridgeman, Esther D. Quakkelaar, Maire F. Quigley, Brenna J. Hill, Maria L. Knudsen, Virginia Ammendola, Karl Ljungberg, Nicola Borthwick, Eung-Jun Im, Andrew J. McMichael, Jan W. Drijfhout, Hui Yee Greenaway, Vanessa Venturi, Daniel C. Douek, Stefano Colloca, Peter Liljeström, Alfredo Nicosia, David A. Price, Cornelis J. M. Melief, and Tomáš Hanke. Long Peptides Induce Polyfunctional T Cells against Conserved Regions of HIV-1 with Superior Breadth to Single-Gene Vaccines in Macaques. Eur. J. Immunol., 40(7):1973-1984, Jul 2010. PubMed ID: 20468055. Show all entries for this paper.


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