HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(146-156) | Gag Epitope Map
View variants at this location |
||||
|---|---|---|---|---|---|---|
| Epitope |
AISPRTLNAWV
|
Epitope Alignment | ||||
| Variants |
|
|||||
| Epitope Name | IW9 | |||||
| Species (MHC/HLA) | human(B*57) | |||||
Showing 1 of 4 variants.
| Variant ID. | 2357 |
|---|---|
| Epitope Seq. | AISPRTLNAWV |
| Variant Seq. | AlSPRTLNAWV |
| Mutations | I/L |
| Epitope Location | I2L |
| HXB2 Location | I147L |
| Mutation Type | OV: observed variant |
| Epitope Subtype | B |
| Variant Subtype | B |
| Method | Sequence |
| Note | One HLA-B*5701 positive patient with low viral load carried this variant, AlSPRTLNAWV, at month 28 after enrollment; One HLA-B*5702 positive patient with low viral load carried it at month 13; and one HLA-B*5703 positive patient with increased viral load carried it from 7 months post-enrollment on. |
Durand2010 Christine M. Durand, Karen A. O'Connell, Linda G. Apuzzo, Susan J. Langan, Hejab Imteyaz, Aima A. Ahonkhai, Christina M. Ceccato, Thomas M. Williams, Joseph B. Margolick, and Joel N. Blankson. HIV-1 Gag Evolution in Recently Infected Human Leukocyte Antigen-B*57 Patients with Low-Level Viremia. AIDS, 24(15):2405-2408, 24 Sep 2010. PubMed ID: 20671542. Show all entries for this paper.