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Found 1 matching record:

Displaying record number 57381

HXB2 Location Gag(77-85) Gag Epitope Map
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Epitope

SLYNTVATL

Epitope Alignment

Variants

SLYNTiATL literature escape

Epitope Name SL9

Species (MHC/HLA) human(A*02:01)

Variant Details

Showing 1 of 3 variants.

Variant ID.	`2342`
Epitope Seq.	`SLYNTVATL`
Variant Seq.	`SLYNTiATL`
Mutations	V/I
Epitope Location	V6I
HXB2 Location	V82I
Mutation Type	LE: literature escape
Epitope Subtype	B
Variant Subtype	B
Method	CD8 T-cell Elispot - IFNy, Chromium-release assay
Note	SL9 variant V82I, SLYNTiATL, was recognized by different TCR mutants with differing functional avidities.

References

Bennett2010 Michael S. Bennett, Aviva Joseph, Hwee L. Ng, Harris Goldstein, and Otto O. Yang. Fine-Tuning of T-Cell Receptor Avidity to Increase HIV Epitope Variant Recognition by Cytotoxic T Lymphocytes. AIDS, 24(17):2619-2628, 13 Nov 2010. PubMed ID: 20881472. Show all entries for this paper.