HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(162-172) | Gag Epitope Map
View variants at this location |
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| Epitope |
KAFSPEVIPMF
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | KF11 | |||||
| Species (MHC/HLA) | human(B*57:01, B*57:03) | |||||
Showing 1 of 6 variants.
| Variant ID. | 224 |
|---|---|
| Epitope Seq. | KAFSPEVIPMF |
| Variant Seq. | KsFSPEtIPMF |
| Mutations | A/S V/T |
| Epitope Location | A2S V7T |
| HXB2 Location | A163S V168T |
| Mutation Type | OV: observed variant |
| Epitope Subtype | C |
| Note | Epitope highly variant in African cohort when restricted by B*5703 but highly conserved in B*5701 European cohort. |
Frater2007 A. J. Frater, H. Brown, A. Oxenius, H. F. Günthard, B. Hirschel, N. Robinson, A. J. Leslie, R. Payne, H. Crawford, A. Prendergast, C. Brander, P. Kiepiela, B. D. Walker, P. J. R. Goulder, A. McLean, and R. E. Phillips. Effective T-Cell Responses Select Human Immunodeficiency Virus Mutants and Slow Disease Progression. J. Virol., 81(12):6742-6751, Jun 2007. PubMed ID: 17409157. Show all entries for this paper.