HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 54629

HXB2 Location  Gag(17-34)   Gag Epitope Map
View variants at this location
Epitope EKIRLRPGGKKKYRLKHL   Epitope Alignment
EKIRLRPGGKKhYmLKHL   subtype-specific susceptible form
Epitope Name GAG-03
Species (MHC/HLA human

Variant Details

Showing all: 1 variant(s).

Variant ID.  1957
Mutations K/H R/M
Epitope Location K12H R14M
HXB2 Location K28H R30M
Mutation Type SSF: subtype-specific susceptible form
Epitope Subtype B
Variant Subtype C
Method CD8 T-cell Elispot - IFNy, Sequence
Note This Clade C consensus synthetic peptide variant from an immunodominant region, differs from the immunodominant Clade B consensus at 2 amino acids (11.1%) and both were recognized by subtype-B-infected subjects.


Zhao2007 Shuguang Zhao, Song Zhai, Yan Zhuang, Shaoyang Wang, Dedong Huang, Whenzhen Kang, Xinhong Li, Xu G. Yu, Bruce D. Walker, Marcus A. Altfeld, and Yongtao Sun. Inter-Clade Cross-Reactivity of HIV-1-Specific T Cell Responses in Human Immunodeficiency Virus Type 1 Infection in China. Curr. HIV Res., 5(2):251-259, Mar 2007. PubMed ID: 17346138. Show all entries for this paper.

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