HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 52791

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
SLYNTVAaL   observed variant
Epitope Name SL9
Species (MHC/HLA human(A2)

Variant Details

Showing 1 of 6 variants.

Variant ID.  1861
Epitope Seq.  SLYNTVATL
Variant Seq.  SLYNTVAaL
Mutations T/A
Epitope Location T8A
HXB2 Location T84A
Mutation Type OV: observed variant
Method Chromium-release assay, Sequence
Note This minority epitope variant was seen after 2 weeks of selection by SL9-specific clone 18030D23.


Yang2003 Otto O Yang, Phuong Thi Nguyen Sarkis, Ayub Ali, Jason D Harlow, Christian Brander, Spyros A Kalams, and Bruce D Walker. Determinant of HIV-1 Mutational Escape from Cytotoxic T Lymphocytes. J. Exp. Med., 197(10):1365-1375, May 2003. PubMed ID: 12743169. Show all entries for this paper.

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