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Found 1 matching record:

Displaying record number 52791

HXB2 Location  Gag(77-85)   Gag Epitope Map
View variants at this location
Epitope SLYNTVATL   Epitope Alignment
Variants
SLYNTiATL   escape documented in this paper
Epitope Name SL9
Species (MHC/HLA human(A2)

Variant Details

Showing 1 of 6 variants.


Variant ID.  1857
Epitope Seq.  SLYNTVATL
Variant Seq.  SLYNTiATL
Mutations V/I
Epitope Location V6I
HXB2 Location V82I
Mutation Type E: escape documented in this paper
Method Chromium-release assay, Sequence
Note After 2 weeks of selective pressure by culturing with 1 of 4 SL9-specific clones i.e. 161JxA14, this variant arose and was not recognized.

References

Yang2003 Otto O Yang, Phuong Thi Nguyen Sarkis, Ayub Ali, Jason D Harlow, Christian Brander, Spyros A Kalams, and Bruce D Walker. Determinant of HIV-1 Mutational Escape from Cytotoxic T Lymphocytes. J. Exp. Med., 197(10):1365-1375, May 2003. PubMed ID: 12743169. Show all entries for this paper.


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