HIV molecular immunology database
Found 1 matching record:
| HXB2 Location | Gag(77-85) | Gag Epitope Map
View variants at this location |
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| Epitope |
SLYNTVATL
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Epitope Alignment | ||||
| Variants |
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| Epitope Name | SL9 | |||||
| Species (MHC/HLA) | human(A2) | |||||
Showing 1 of 6 variants.
| Variant ID. | 1857 |
|---|---|
| Epitope Seq. | SLYNTVATL |
| Variant Seq. | SLYNTiATL |
| Mutations | V/I |
| Epitope Location | V6I |
| HXB2 Location | V82I |
| Mutation Type | E: escape documented in this paper |
| Method | Chromium-release assay, Sequence |
| Note | After 2 weeks of selective pressure by culturing with 1 of 4 SL9-specific clones i.e. 161JxA14, this variant arose and was not recognized. |
Yang2003 Otto O Yang, Phuong Thi Nguyen Sarkis, Ayub Ali, Jason D Harlow, Christian Brander, Spyros A Kalams, and Bruce D Walker. Determinant of HIV-1 Mutational Escape from Cytotoxic T Lymphocytes. J. Exp. Med., 197(10):1365-1375, May 2003. PubMed ID: 12743169. Show all entries for this paper.