HIV molecular immunology database


Search the Epitope Variant and Escape Mutation Database


Found 1 matching record:

Displaying record number 5

HXB2 Location  Gag(18-26)   Gag Epitope Map
View variants at this location
Epitope KIRLRPGGK   Epitope Alignment
rIRLRPGGr   escape documented in this paper
Species (MHC/HLA human(A3)

Variant Details

Showing 1 of 2 variants.

Variant ID.  1839
Epitope Seq.  KIRLRPGGK
Variant Seq.  rIRLRPGGr
Mutations K/R K/R
Epitope Location K1R K9R
HXB2 Location K18R K26R
Mutation Type E: escape documented in this paper
Method Chromium-release assay
Note This escape was not recognized by HIV-transmitting mothers


Wilson1999a C. C. Wilson, R. C. Brown, B. T. Korber, B. M. Wilkes, D. J. Ruhl, D. Sakamoto, K. Kunstman, K. Luzuriaga, I. C. Hanson, S. M. Widmayer, A. Wiznia, S. Clapp, A. J. Ammann, R. A. Koup, S. M. Wolinsky, and B. D. Walker. Frequent Detection of Escape from Cytotoxic T-Lymphocyte Recognition in Perinatal Human Immunodeficiency Virus (HIV) Type 1 Transmission: The Ariel Project for the Prevention of Transmission of HIV from Mother to Infant. J. Virol., 73:3975-3985, 1999. PubMed ID: 10196293. Show all entries for this paper.

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