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Found 1 matching record:

Displaying record number 55002

HXB2 Location  Gag(147-155)   Gag Epitope Map
View variants at this location
Epitope ISPRTLNAW   Epitope Alignment
Variants
vSPRTLNAW   non-susceptible form; susceptible form
Epitope Name ISP
Species (MHC/HLA human(B*57:01)

Variant Details

Showing 1 of 8 variants.


Variant ID.  1791
Epitope Seq.  ISPRTLNAW
Variant Seq.  vSPRTLNAW
Mutations I/V
Epitope Location I1V
HXB2 Location I147V
Mutation Type NSF: non-susceptible form
SF: susceptible form
Method CD8 T-cell Elispot - IFNy, Tetramer binding
Note Some patients recognized the variant, some did not.

References

Turnbull2006 Emma L. Turnbull, A. Ross Lopes, Nicola A. Jones, David Cornforth, Phillipa Newton, Diana Aldam, Pierre Pellegrino, Jo Turner, Ian Williams, Craig M. Wilson, Paul A. Goepfert, Mala K. Maini, and Persephone Borrow. HIV-1 Epitope-Specific CD8+ T Cell Responses Strongly Associated with Delayed Disease Progression Cross-Recognize Epitope Variants Efficiently. J. Immunol., 176(10):6130-6146, 15 May 2006. PubMed ID: 16670322. Show all entries for this paper.


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