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Displaying record number 55002

HXB2 Location Gag(147-155) Gag Epitope Map
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Epitope

ISPRTLNAW

Epitope Alignment

Variants

mSPRTLNAW non-susceptible form; susceptible form

Epitope Name ISP

Species (MHC/HLA) human(B*57:01)

Variant Details

Showing 1 of 8 variants.

Variant ID.	`1790`
Epitope Seq.	`ISPRTLNAW`
Variant Seq.	`mSPRTLNAW`
Mutations	I/M
Epitope Location	I1M
HXB2 Location	I147M
Mutation Type	NSF: non-susceptible form SF: susceptible form
Method	CD8 T-cell Elispot - IFNy, Tetramer binding
Note	Some patients recognized the variant, some did not.

References

Turnbull2006 Emma L. Turnbull, A. Ross Lopes, Nicola A. Jones, David Cornforth, Phillipa Newton, Diana Aldam, Pierre Pellegrino, Jo Turner, Ian Williams, Craig M. Wilson, Paul A. Goepfert, Mala K. Maini, and Persephone Borrow. HIV-1 Epitope-Specific CD8+ T Cell Responses Strongly Associated with Delayed Disease Progression Cross-Recognize Epitope Variants Efficiently. J. Immunol., 176(10):6130-6146, 15 May 2006. PubMed ID: 16670322. Show all entries for this paper.