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Found 1 matching record:

Displaying record number 55002

HXB2 Location  Gag(147-155)   Gag Epitope Map
View variants at this location
Epitope ISPRTLNAW   Epitope Alignment
Variants
raPRTLNAW   non-susceptible form
Epitope Name ISP
Species (MHC/HLA human(B*57:01)

Variant Details

Showing 1 of 8 variants.


Variant ID.  1789
Epitope Seq.  ISPRTLNAW
Variant Seq.  raPRTLNAW
Mutations I/R S/A
Epitope Location I1R S2A
HXB2 Location I147R S148A
Mutation Type NSF: non-susceptible form
Method CD8 T-cell Elispot - IFNy, Tetramer binding
Note None of the patients tested recognized the variant.

References

Turnbull2006 Emma L. Turnbull, A. Ross Lopes, Nicola A. Jones, David Cornforth, Phillipa Newton, Diana Aldam, Pierre Pellegrino, Jo Turner, Ian Williams, Craig M. Wilson, Paul A. Goepfert, Mala K. Maini, and Persephone Borrow. HIV-1 Epitope-Specific CD8+ T Cell Responses Strongly Associated with Delayed Disease Progression Cross-Recognize Epitope Variants Efficiently. J. Immunol., 176(10):6130-6146, 15 May 2006. PubMed ID: 16670322. Show all entries for this paper.


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