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Displaying record number 55002

HXB2 Location Gag(147-155) Gag Epitope Map
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Epitope

ISPRTLNAW

Epitope Alignment

Variants

raPRTLNAW non-susceptible form

Epitope Name ISP

Species (MHC/HLA) human(B*57:01)

Variant Details

Showing 1 of 8 variants.

Variant ID.	`1789`
Epitope Seq.	`ISPRTLNAW`
Variant Seq.	`raPRTLNAW`
Mutations	I/R S/A
Epitope Location	I1R S2A
HXB2 Location	I147R S148A
Mutation Type	NSF: non-susceptible form
Method	CD8 T-cell Elispot - IFNy, Tetramer binding
Note	None of the patients tested recognized the variant.

References

Turnbull2006 Emma L. Turnbull, A. Ross Lopes, Nicola A. Jones, David Cornforth, Phillipa Newton, Diana Aldam, Pierre Pellegrino, Jo Turner, Ian Williams, Craig M. Wilson, Paul A. Goepfert, Mala K. Maini, and Persephone Borrow. HIV-1 Epitope-Specific CD8+ T Cell Responses Strongly Associated with Delayed Disease Progression Cross-Recognize Epitope Variants Efficiently. J. Immunol., 176(10):6130-6146, 15 May 2006. PubMed ID: 16670322. Show all entries for this paper.